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KMID : 0361520070180010018
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Korean Journal of Psychopharmacology
2007 Volume.18 No. 1 p.18 ~ p.24
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Intravenous Anti-obsessive Agents：A Review
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Kim Mi-Kyung
Jung Sun-Min
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Abstract
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Oral (p.o.) administration has a delayed onset time of several weeks and moderate efficacy in obsessive-compulsive disorder (OCD), therefore a more rapidly effective treatment is required. The aim of this paper was to review available data detailing the clinical outcome of intravenously (i.v.) administered antiobsessional drug in OCD patients. Review of the research indicates that i.v. administration exhibits a faster onset and greater improvement than p.o. administration. I.v. pulse administration showed clinically significantly faster onset than i.v. gradual administration. I.v. administration was safe and rapidly effective in treatment resistant OCD patients and might be a valuable new treatment.
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KEYWORD
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Obsessive-compulsive disorder, pIntravenous administration, Clomipramine, Citalopram
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